Khatri P, Sirota M, Butte AJ (2012) Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges. Overview of existing pathway analysis methods using gene expression data as an example. Bioinformatics : doi: /bioinformatics/bti565 Copyright restrictions may apply.ġ9 Gene Lists Microarrays Protein arrays CHIP-chip SNP arrays RNA SeqĢ1 DAVID Tools Functional Annotation Clustering Chart – Term centricĢ5 Figure 1. A workflow is a convenient way to automate your own analysis pipeline or to distribute it to colleagues. A workflow consists of a series of tools in which the output of one tool is connected to and used as the input of another tool. CLC Genomics was acquired with funds provided by ORIED as well as participating groups of faculty that lobbied for its acquisition. This tutorial takes you through how to set up and run a workflow in the CLC Genomics Workbench. PLOS Computational Biology 8(2): eġ7 Cellular Component Biological Process Molecular Function GO Annotationġ8 Gene Ontology (GO) Levels of abstraction Getting Up and Running with CLC Genomics Workbench at NC State University Introduction: This resource guide is intended to help NC State users of CLC Genomics Workbench access and utilize this powerful software suite. Khatri P, Sirota M, Butte AJ (2012) Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges. QIAGEN CLC Genomics Workbench is widely used for a variety of pipelines including but not limited to RNA-seq, single-cell RNA-seq, variant calling (SNPs, CNV, indels, etc. Overview of existing pathway analysis methods using gene expression data as an example. CLC Genomics Workbench 23.0.2 is for research purposes only. IPA Enriched Pathways, Functions, Diseases, Upstream Regulators Correlation Engine GEO Correlated Studies +ve and -ve DEX vs UNT DEGġ6 Figure 1. Learn How to … Draw Pathway Diagram : ePath3D, Chem Office, Search PPI Databases: BioGrid, STRING Search Gene Expression Databases: Correlation Engine Find Statistically Overrepresented Attribute Linked to Differentially Expressed Genes: IPA, DAVID,Įnrichment Analysis Deferentially Expressed Genes CLC Genomics Work Bench Ingenuity Pathway Analysis Functions Diseases Pathways RNA-Seq Reads Key Pathway Advisor Upstream Regulators Any Organism Volcano Plot PCA Plot Venn Diagram Heat Map Illumina BaseSpace Correlation Engine Correlated Expression Studies CLC BioMedical Work Bench Variant Detection Ingenuity Variant Analysis Human, Mouse and Rat Variant Annotation and Prioritization RNA-Seq Analysis Down Stream Analysisĩ RNA-Seq Workshop FASTq Reads CLC Genomics WorkBench Presentation on theme: "Pathway Informatics 16th August, 2017"- Presentation transcript:Īnsuman Chattopadhyay, PhD Molecular Biology Information Services Health Sciences Library System University of Pittsburghģ Software Search Gene Expression Databases: Correlation Engine CLC Genomics Workbench is software for analyzing and visualizing next generation sequencing data.
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Of those, over 115 are owned by local SigEp Alumni and Volunteer Corporations. Sigma Phi Epsilon has the greatest number of fraternity houses, with over 200 chapter homes. SigEp was the first national fraternity to establish a housing trust for all chapters and create a National Housing Corporation. SigEp hosts the largest biennial convention in the fraternity world: the Grand Chapter Conclave. The SigEp Journal has been published continuously since 1904, and is distributed to all members for life. SigEp maintains a full-time professional staff of over 35 people. Nearly 300,000 lifetime members ranks SigEp among the largest national fraternities. Currently, more than 15,000 undergraduates are SigEps, more than any other national fraternity. Over the past two decades, SigEp has recruited more men than any other collegiate fraternity. SigEp was founded on November 1, 1901, at Richmond College. Into the New Millennium: From 2000-present day Second 50 Years: From the 1950s through 2000 Pick a time period below and learn more about SigEp’s legacy:įirst 50 Years: From 1901 through the 1940s Throughout the decades, the men of Sigma Phi Epsilon have practiced their values and embraced the stated desire of the Founders, “This Fraternity will be different.” Today, the University of Richmond campus features the Sigma Phi Epsilon Founders Walk, (pictured below) a path in the center of campus that honors the 12 men who started what would become one of the nation’s largest fraternities. The history of the Fraternity reflects the times, through great wars and profound cultural shifts. About 75% of our members participate in and hold leadership positions in various campus organizations and professional fraternities. Our chapter is home to 70 brothers who study a variety of subjects from all 7 colleges at Cornell. From the very first days, the chapter developed a strong year-round recruitment process, an exciting and involved member development program, and a meaningful relationship with the Alumni Volunteer Corporation (AVC). In 2006, the National Headquarters staff and a determined alumni base worked to bring SigEp back to Cornell based on the Balanced Man model. In 1966, the fraternity voted to move to 109 McGraw Place, and SigEp maintained a strong presence on campus up until 2005. The Cornell chapter grew very quickly, while maintaining the fraternity values that we continue to uphold today. By 1912, it found itself in need of change and it took the opportunity to merge with the growing national fraternity to become the New York Beta Chapter of Sigma Phi Epsilon. Our roots can be traced back to 1903, when a small law fraternity named Theta Lambda Phi stood at 112 Edgemoore Lane near Collegetown. Sigma Phi Epsilon has a long standing tradition here at Cornell. While maintaining focus on academics, all members of SigEp are involved in their individual pursuit of key lessons contained in various Balanced Man challenges - a process that builds knowledge and experience in their roles and responsibilities as members of the fraternity, larger community, and world - preparing them for meaningful life as capable leaders, citizens, employees, and parents. Our New York Beta chapter has the tenth highest GPA on campus at a 3.476. After nearly a century, SigEp is now the nation's largest fraternity, boasting over 270 chapters throughout North America, 255,000 supportive alumni, and the nation's highest all-chapter GPA, which is over a 3.1. Started in December of 1901, the dream of Carter Ashton Jenkens and eleven other men became a reality as the Sigma Phi Epsilon fraternity was born at Richmond College in Virginia. About Us First 100 Years :: Our Home :: Activities :: Officers "Pets are part of the family structure," Smith told ABC News at the conclusion of the Washington, D.C., press conference. Aminopterin, a derivative of folic acid, is sometimes used as a rodenticide, though such use is banned in the United States and Canada. However, Smith and Stephen Sundlof, the FDA's chief veterinarian, noted at the Washington press conference that neither Cornell nor the FDA could confirm the presence of aminopterin in samples. Smith participated in that press conference because the samples of pet food tested by the Albany laboratory had been supplied by Cornell researchers during an early phase of the investigation. 3, 2006, to March 6, 2007.Īt a press conference in Albany on March 23, researchers at the New York State Agriculture and Markets Food Laboratory reported they had found a toxin called aminopterin in two out of three pet food samples provided by Menu Foods. On March 16, Menu Foods issued a massive recall of 60 million cans and pouches of pet food packaged from Dec. Menu Foods, the pet food maker for 95 top brands of "wet" pet foods, initially contacted Cornell's Animal Health Diagnostic Center to test pet food samples after six cats in one of their food trials died from kidney failure. He also cited collaborations with other universities and private laboratories, including Advion, in Ithaca. Smith noted that Cornell has been playing a leading role in trying to identify the toxic properties of the contaminated food and in attempting to understand what might be causing the kidney failure. He specifically referred to signs of acute damage to the tubules and the characteristic pattern of cellular inflammation that have been seen in affected kidneys. However, Smith emphasized, Cornell researchers have not been able to match the known toxic effects of melamine with all of the clinical and pathologic signs observed in affected cats and dogs. Veterinarians across the country have reported hundreds of cases of kidney failure in pets.ĭuring the press conference, which was shown on CNN, Smith displayed photographs of the urinary tract crystals from affected animals that have been seen by clinicians and pathologists in many parts of the country, and he also showed a microscopic image of an affected kidney. The deaths of 15 pets nationwide - one dog and 14 cats - have been confirmed by Menu Foods, the pet food maker. Smith also reported that Cornell had identified melamine in urine of affected cats and in the kidney of one cat that had died after eating the contaminated food. Food and Drug Administration (FDA) March 30 press conference in Washington, D.C., to announce that both Cornell and the FDA had independently identified a contaminant called melamine in samples of recalled pet food and in suspect wheat gluten used in its manufacture. This electron microscope image shows crystals of the type found in the urinary tracts of cats affected by recently discovered pet food contaminants.Ĭornell College of Veterinary Medicine Dean Donald Smith joined a panel of experts at a U.S. Therefore test that on your machine and decide how to set tocrlf.īelow description from git config about tocrlf is incorrect:
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So, like using AirPlay on an iPad or iPhone, it's an indirect method of streaming, with the disadvantage of networked audio file tracks actually going to the Android device to be played by the app you are using on it, rather than going directly to be played by the Chromecast Audio itself, from the internet music service's online server or your own media server on a networked device like a NAS or computer.įurthermore and unlike AirPlay, which specifies the lossless ALAC audio encoding fixed at the CD-res of 16bit/44.1kHz for its audio streams, there's no mention that the audio being streamed will be using a lossless encoding method (so could well be using a lossy audio encoding like MP3 or AAC with a bandwidth saving low bitrate), putting the audio quality of the cast screen/audio Google Cast streaming method in doubt.Ī workaround is still a workaround, even if it's not by a third party!Ĭlick to expand.That's not quite what I said. Well done, Xanthe, over at Naim Forums for figuring it out and for letting the people know how to do it (the post was actually from October last year)!Ĭlaiming that the Google Home app's/Android's built-in cast screen/audio Google Cast streaming method to a Chromecast Audio supports gapless playback is a bit like saying Apple's AirPlay to an AirPlay device supports gapless playback.Īll you are doing is relying on the particular music app's internal audio player to do the actual gapless playback of the tracks in the playlist and then getting the resulting audio output (that would normally go to the Android device's internal DAC and then out to its speakers) to be streamed via Google Cast out to the Chromecast Audio. I don't seem to be able to achieve gapless playback from my Macbook Air using the casting option built into Chrome, and I haven't tried to achieve it on a Windows machine either, so I can't say for sure whether gapless playback is or isn't doable on those platforms.įwiw, I've read lots and lots of pages on the web over the years hoping to find a solution to get gapless playback on my CCA but the post I read yesterday morning is the first and only one I've ever come across stating that CCA does support gapless playback (without having to utilise third-party workarounds like HiFi Cast) and that this is the very simple way to do it I should add, I ran into problems when I tried using an old Android device whereby the Google Home app is limited to an old, unsupported version (version 2.29.1.7) the version on my other Android device (version 2.32.1.5) works perfectly. I've tested this with PLEX and Poweramp and both options work fine. The solution is simple: initiate casting via the Google Home app first then open your media player and play music - it's that simple! For years I've been using the PLEX app to cast to my CCA and for years (or for some time at least) I've been missing out on gapless playback. One of the key missing jigsaw pieces in my streaming setup is finally missing no more: Chromecast Audio supports gapless playback, and apparently, it has done for time! Added Save As (Alt+S) command to EditorĮditor only prompts for a file name when necessary (i.e.Added option " If draw objects exist, auto-save a copy in FSC format for re-editing".Window even without a vertical scroll bar Now you can capture any part of a scrolling > Notifications tab, you can customize the color and size Simply click and drag from the beginning or end of the timeline Which allows you to insert title pages anywhere in the video clip You can use it to convert or resize video files (WMVĪnd recover a screen recording from an unexpected Windows Support touch interface (tap, swipe, pinch)įormat for Screen Recorder on Windows 10/11.Support high-DPI/high-resolution/ 4K monitors.Auto capture screen repeatedly at user-specified time intervals.Combine images into a single image file.Proprietary and loss-less format that preserves annotation objects together with image data for future re-editing Save images in FSC (FastStone Capture) format, a.Save images in BMP, GIF, JPEG, PCX, PNG, TGA, TIFF and PDF.Each workspace remembers its last-used folder and works like a separate instance of the internal editor Support tabs that allow you to capture and edit.Resize, crop, rotate, sharpen, brighten,.Apply effects such as spotlight, drop-shadow, frame, torn-edge and fade-edge.Draw annotation objects such as callouts, straight/curvedĪrrowed lines, highlights, watermarks, rectangles, circles, step numbers,.(internal editor, clipboard, file, printer. Under various resolution and quality options To MP4" tool that converts or resizes video files (MP4 and WMV) Videos can even be converted to animated gifs That allows you to draw annotations, apply zoom effects and cut Screen Recorder has a built-in video editor.Onscreen changes, speech from microphone, audio from speakers, mouse movements and clicks into highly compressed video files A handy Capture Panel that provides quick access to its capture tools and output optionsįull screen, rectangular/ freehand/ fixed-size.Built-in screen recorder saves videos in MP4 and WMV formats. Other features include image scanning, global hotkeys, automatic filename generation, support for external editors, a color picker, a screen magnifier,įastStone Capture saves images in BMP, GIF, JPEG, PCX, PNG, TGA, TIFF,įormats. Editing tools include annotating (texts, arrowed lines, highlights), resizing, cropping, sharpening, watermarking, applying edge effects and many more. OneNote / Word / Excel / PowerPoint document or upload them to your website. You can choose to send captures to editor, file, clipboard, printer, email, It also allows you to record all screen activities including onscreen changes, speech from microphone,Īudio from speakers, mouse movements and clicks into highly compressed video files. Rectangular / freehand / fixed regions as well as scrolling windows / It allows you to easily capture and annotate anything on the screen including windows, objects, menus, full screen, These methods included measuring the amount of time between when each model was discontinued and when it stopped receiving updates, which is particularly relevant for models like the 2013 Mac Pro, 2014 Mac mini, and 2015 MacBook Air that were sold for multiple years after they were first introduced. Hoping that the current test cycle is coming to an end, the apple released today in Launch Candidates (RC) of iOS 16.4 (Compilation 20E246 ), of the iPadOS 16.4 (idem), do macOS Venture 13.3 ( 22E252 ), of the watch OS 9.4 ( 20T253) It is TvOS 16. The end result is a spreadsheet full of dozens of Macs, with multiple metrics for determining how long each one received official software support from Apple. Step 10: In the window, select the model of your Mac. Click macOS Post Install in the side menu or the drop-down menu in Utilities. Step 9: Let the installation finish, and once it is completed, reboot back into the installer drive (same as Step 5). (I've made some notes on how I chose to streamline and organize the data, which I've put at the end of this article). Select where you want to install macOS and click Continue. 10.4.11, 11.6) and their last regular security patches. We recorded when each model was released, when Apple stopped selling each model, the last officially supported macOS release for each system, and the dates when those versions of macOS received their last point updates (i.e. For complete specs on a particular system, click the name of the Mac. In addition, you must update your iPhoto '11 software on your Mac with the latest. These files are designed for popular Apple devices like the iPhone and iPod. installed on your Mac, and have the most current version of iTunes. Using data from Apple's website and, we pulled together information on more than two decades of Mac releases-almost everything Apple has released between the original iMac in late 1998 and the last Intel Macs in 2020. iOS for Mac is really just a group of firmware update files, which are called IPSWs. But how bad is it, really? Is a Mac purchased in 2016 getting fewer updates than one bought in 2012 or 2008 or 1999? And if so, is there an explanation beyond Apple's desire for more users to move to shiny new Apple Silicon Macs? This certainly seems more aggressive than new macOS releases from just a few years ago, where system requirements would tighten roughly every other year or so. Ventura requires a Mac made in 2017 or later, dropping support for a wide range of Monterey-supported Mac models released between 20. When macOS Ventura was announced earlier this month, its system requirements were considerably stricter than those for macOS Monterey, which was released just eight months ago as of this writing. Further Reading macOS 13 Ventura dumps all pre-2017 Macs, including the “trash can” Mac Pro With a push of the button on the side, you can hear the turret talk, just like in the game. Portal Turret LED Flashlight with Sound – Standing just 3” tall, this intricately detailed replica of the Turret enemies will light your way with a red LED beam, emanating from the Turret’s eye.You provide the potato and some simple assembly. Portal 2 PotatOS Science Kit – Create your own GLaDOS with a PotatOS Science Kit including electronic talking GLaDOS module.Wheatley LED Flashlight – A 2” tall version of the smart talking Wheatley character, simply push a button, and a super-bright LED flashlight emanates from Wheatley’s “eye” to illuminate your surroundings.Start assembling your Turret army for just $34.99. To “disable” it, you just tip it over like you would in the game. When sensing motion, the Portal 2 Plush Turret reacts with voice and simulated machine gun fire. Portal 2 Plush Turret with Sound – A classic character from Portal video game series, this Turret features motion detection, light, sound and vibration.One end shows the Portal test subject icon entering through an orange entry portal, while the other end shows him exiting through a blue exit portal. Portal Bookends – 4”x5” solid metal bookends to maintain the vertical orientation your impressive collection of science textbooks.The Portal Cookie Cutters feature an all metal construction and come in a collectible Companion Cube tin. So fill up your new Companion Cube Cookie Jar with delicious treats inspired by the “warning signs” featured in the game. Portal Cookie Cutters – Of course, a cookie jar without cookies is like an empty test chamber in your soul.Portal Companion Cube Cookie Jar – A replica of the Weighted Companion Cube that makes a prominent appearance as an inanimate, but lovable, puzzle solving device in the original Portal.This collectible curtain is available now for $19.99. ThinkGeek presents gamers with their very own Aperture Science shower curtain to transform their bathroom into a test chamber. Aperture Laboratories Shower Curtain – At long last, fans of Aperture Laboratories can put their hands on the product that started it all: military-grade shower curtains.Sorry, looks like you failed this task! Never mind, Cave Johnson will let you continue.Valve and ThinkGeek have teamed up to give us nine new Portal 2 products including a turret plushie with sound, Wheatley LED flashlight, cookie cutters, Cave Johnson talking portrait, and more. You can head on to the next test chamber. In fact, when the red sensor in the middle lights up, it means it wants to say "I love you." And it even occasionally starts to vibrate with joy, just because you're there!Īll right, test's over. The Plush Turret might not be the best at expressing feelings, but it does loves you, really. Accompanied by the sound of dual machine guns. This first test involves something the lab boys call Portal 2 Plush Turret with light and sound.ĭon't be afraid, Cave Johnson will be with you as you try to solve your first task: Try to pass by this fluffy plush turret without hugging it! That's not as easy as it sounds on account of its motion sensor, which will become aware of you as soon as you get close and then start to talk to you. So: who is ready to make some science?Īre you ready? Then enter the test chamber!Īlright, let's get started. Astronauts, war heroes, Olympians – you're here because we want the best, and you are it. |